NIH scientists and collaborators find infectious prion protein in skin of CJD patients

Discuss the things that affect the cattle industry.
flounder
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NIH scientists and collaborators find infectious prion protein in skin of CJD patients

Postby flounder » Thu Nov 23, 2017 1:21 pm

-----Original Message-----
From: Terry Singeltary <flounder9@verizon.net>
To:
Sent: Thu, Nov 23, 2017 10:22 am
Subject: re-NIH scientists and collaborators find infectious prion protein in skin of CJD patients

>>>Although sCJD patient skin contained ~103- to 105-fold lower prion seeding activity than did sCJD patient brain tissue, all 12 mice from two transgenic mouse lines inoculated with sCJD skin homogenates from two sCJD patients succumbed to prion disease within 564 days after inoculation<<<

for something to be 103 to 105 fold lower prion seeding, yet still be 100% fatal in all test subjects, very disturbing...terry

WEDNESDAY, NOVEMBER 22, 2017

NIH scientists and collaborators find infectious prion protein in skin of CJD patients

http://creutzfeldt-jakob-disease.blogsp ... -find.html

WEDNESDAY, NOVEMBER 22, 2017

Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease

http://creutzfeldt-jakob-disease.blogsp ... ivity.html

back to reality...

Thursday, November 16, 2017

Texas Natural Meats Recalls Beef Products Due To Possible Specified Risk Materials Contamination

http://specifiedriskmaterial.blogspot.c ... -beef.html

SATURDAY, NOVEMBER 4, 2017

FDA 589.2000, Section 21 C.F.R. Animal Proteins Prohibited in Ruminant Feed WARNING Letters and FEED MILL VIOLATIONS OBSERVATIONS 2017 to 2006

http://bovineprp.blogspot.com/2017/11/f ... nimal.html

FRIDAY, NOVEMBER 3, 2017

BSE MAD COW TSE PRION DISEASE PET FOOD FEED IN COMMERCE INDUSTRY VS TERRY S. SINGELTARY Sr. A REVIEW

''I have a neighbor who is a dairy farmer. He tells me that he knows of several farmers who feed their cattle expired dog food. These farmers are unaware of any dangers posed to their cattle from the pet food contents. For these farmers, the pet food is just another source of protein.''

IN CONFIDENCE

http://madcowfeed.blogspot.com/2017/11/ ... -food.html
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Hook2.0
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Re: NIH scientists and collaborators find infectious prion protein in skin of CJD patients

Postby Hook2.0 » Mon Nov 27, 2017 5:29 am

"From: "Terry S. Singeltary Sr."

Reply-To: Bovine Spongiform Encephalopathy

Date: Fri, 17 Aug 2001 09:27:27 -0700

Content-Type: text/plain Parts/Attachments: Parts/Attachments text/plain (223 lines) Reply Reply

######## Bovine Spongiform Encephalopathy #########

Greetings Todd, Nancy, Robert, and other List Members,

i sat in on the June 9, 2001 emergency BSE Conference call between the 50 states. believe me when i tell you, most of the farmers are ignorant to the ruminant-to-ruminant feed ban, and the others simply refuse to understand the true risk, and refuse to adhere to the rules. the FDA cannot enforce, so the next best thing we can hope for, is that the cows, pigs, deer elk and chickens take a reading course, so they themselves can read the labels, because the farmers cannot, and others simply will not. most folks just do not take this seriously in 2001.

i remember one of the recent news reports on T.V. and they were interviewing some cowboy at a auction house where his cattle were being auctioned. typical cowboy, big, fat, and had a big chew in his mouth. the auctioneer was doing his thing, and the news reporter walked up to this cowboy and asked him what he thought of the madcow problem. he said, ''awe, they just maken this stuff up''. simply put, he did not believe it existed. i am afraid that this is the way many of the cowboys/ranchers think. This is a frightening thought, and this is still happening in 2001. SO, we are better off teaching all farm animals to read...
"

Interesting viewpoint terry
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Son of Butch
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Re: NIH scientists and collaborators find infectious prion protein in skin of CJD patients

Postby Son of Butch » Tue Nov 28, 2017 2:28 am

So What?

What are we talking something like a dozen confirmed deaths in USA in 30 years and most or all from
contamination during hospital procedures?

But sorry for the loss of your mother 20 years ago.


p.s.
As your mission is to teach farm animals to read make sure you point out to them there is a difference between
infectious and contagious or even they may accuse you of fear mongering.
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flounder
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Re: NIH scientists and collaborators find infectious prion protein in skin of CJD patients

Postby flounder » Tue Nov 28, 2017 10:28 am

actually, in 55 year old and greater, the rate of death for sporadic cjd is one in 9,000.

sporadic cjd has now been linked to typical and atypical BSE, typical and atypical Scrapie, and now to CWD in cervid.

Alzheimer's has now been linked to TSE Prion.

iatrogenic, threat becoming more and more likely.

you do the math.

MONDAY, NOVEMBER 06, 2017

Experimental transfusion of variant CJD-infected blood reveals previously uncharacterised prion disorder in mice and macaque

''On secondary and tertiary transmissions, however, the proportion of PrPres positive animals gradually increased to almost 100%.

''Recent communications suggest that a similar situation might exist in other models of experimental exposure to prions involving swine32 and cattle33.''

''Experimental transfusion of variant CJD-infected blood reveals previously uncharacterised prion disorder in mice and macaque''

http://vcjd.blogspot.com/2017/11/experi ... t-cjd.html

THURSDAY, AUGUST 17, 2017

*** Monitoring the occurrence of emerging forms of Creutzfeldt-Jakob disease in the United States revisited 2017 Singeltary et al

http://creutzfeldt-jakob-disease.blogsp ... forms.html

WEDNESDAY, NOVEMBER 1, 2017

Blood-derived amyloid-β protein induces Alzheimer’s disease pathologies

http://betaamyloidcjd.blogspot.com/2017 ... duces.html

Commentary: Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

http://journals.plos.org/plosone/articl ... 6882c30f9d

https://www.frontiersin.org/articles/10 ... 00005/full

Diagnosis and Reporting of Creutzfeldt-Jakob Disease

Singeltary, Sr et al. JAMA.2001; 285: 733-734. Vol. 285 No. 6, February 14, 2001 JAMA Diagnosis and Reporting of Creutzfeldt-Jakob Disease

To the Editor:

In their Research Letter, Dr Gibbons and colleagues1 reported that the annual US death rate due to Creutzfeldt-Jakob disease (CJD) has been stable since 1985. These estimates, however, are based only on reported cases, and do not include misdiagnosed or preclinical cases. It seems to me that misdiagnosis alone would drastically change these figures. An unknown number of persons with a diagnosis of Alzheimer disease in fact may have CJD, although only a small number of these patients receive the postmortem examination necessary to make this diagnosis. Furthermore, only a few states have made CJD reportable. Human and animal transmissible spongiform encephalopathies should be reportable nationwide and internationally.

Terry S. Singeltary, Sr Bacliff, Tex

1. Gibbons RV, Holman RC, Belay ED, Schonberger LB. Creutzfeldt-Jakob disease in the United States: 1979-1998. JAMA. 2000;284:2322-2323.

http://jama.jamanetwork.com/article.asp ... id=1031186
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