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NCBA, R-CALF, COOL, USDA (No Politics!)
WAHIS Brazil Bovine spongiform encephalopathy Follow up report 1 [FINAL]
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<blockquote data-quote="flounder" data-source="post: 1792057" data-attributes="member: 3519"><p>WAHIS Brazil Bovine spongiform encephalopathy Follow up report 1 [FINAL]</p><p></p><p>Brazil - Bovine spongiform encephalopathy - Follow up report 1 [FINAL]</p><p></p><p>GENERAL INFORMATION</p><p></p><p>COUNTRY/TERRITORY OR ZONE</p><p></p><p>COUNTRY/TERRITORY</p><p></p><p>ANIMAL TYPE TERRESTRIAL</p><p></p><p>DISEASE CATEGORY OIE-listed</p><p></p><p>EVENT ID 4918</p><p></p><p>DISEASE Bovine spongiform encephalopathy</p><p></p><p>CAUSAL AGENT Bovine spongiform encephalopathy prion, atypical strain, H-type</p><p></p><p>GENOTYPE / SEROTYPE / SUBTYPE -</p><p></p><p>START DATE 2023/01/18</p><p></p><p>REASON FOR NOTIFICATION Recurrence of an eradicated disease</p><p></p><p>DATE OF LAST OCCURRENCE 2021/09/03</p><p></p><p>CONFIRMATION DATE 2023/02/22</p><p></p><p>EVENT STATUS Resolved</p><p></p><p>END DATE 2023/03/03</p><p></p><p>SELF-DECLARATION NO</p><p></p><p>REPORT INFORMATION REPORT NUMBER Follow-up report 1</p><p></p><p>REPORT ID FUR_159644</p><p></p><p>REPORT REFERENCE -</p><p></p><p>REPORT DATE 2023/03/05</p><p></p><p>REPORT STATUS Validated</p><p></p><p>NO EVOLUTION REPORT -</p><p></p><p>EPIDEMIOLOGY</p><p></p><p>SOURCE OF EVENT OR ORIGIN OF INFECTION</p><p></p><p>Unknown or inconclusive</p><p></p><p>EPIDEMIOLOGICAL COMMENTS</p><p></p><p>On March 3rd, 2023, the National Centre for Animal Diseases/Canadian Food Inspection Agency (NCAD/CFIA), Lethbridge Laboratory, WOAH reference laboratory, issued a conclusive result of the Western Blotting test with atypical H-type BSE detected. This is the sixth case of atypical H-type BSE registered in Brazil in more than 25 years of surveillance for the disease. Brazil has never diagnosed a classical BSE case, maintaining, since 2012, official recognition by the WOAH as a country of negligible risk for the disease. The investigation has been completed.</p><p></p><p>QUANTITATIVE DATA SUMMARY MEASURING UNIT Animal</p><p></p><p>Species Susceptible Cases Deaths Killed and Disposed of Slaughtered/ Killed for commercial use Vaccinated</p><p></p><p>Cattle (DOMESTIC) NEW------</p><p></p><p>TOTAL160 1 0 1 0 0 DIAGNOSTIC DETAILS CLINICAL SIGNS YES</p><p></p><p>METHOD OF DIAGNOSTIC Diagnostic test</p><p></p><p>Test name Laboratory Species sampled Number of outbreaks sampled First result date Latest result date Result</p><p></p><p>Antigen detection Western blot (Ag Western blot) Canadian Food Inspection Agency (CFIA), National Centre for Animal Disease (NCAD), Lethbridge Laboratory Cattle 1 2023/03/03 2023/03/03 Positive</p><p></p><p>Immunohistochemistry (IHC) Laboratorio Federal de Defesa Agropecuária - PE Cattle 1 2023/02/22 2023/02/22 Positive</p><p></p><p>CONTROL MEASURES AT EVENT LEVEL</p><p></p><p>CONTROL MEASURES AT EVENT LEVEL</p><p></p><p>DOMESTIC ANIMALS</p><p></p><p>WILD ANIMALS</p><p></p><p>Official disposal of carcasses, by-products and waste</p><p></p><p>Applied</p><p></p><p>Screening</p><p></p><p>Applied</p><p></p><p>Selective killing and disposal</p><p></p><p>Applied</p><p></p><p>Traceability</p><p></p><p>Applied</p><p></p><p>PREVIOUSLY REPORTED OUTBREAKS</p><p></p><p>OB_114504 - 15042080057 - MARABÁ</p><p><a href="https://wahis.woah.org/#/in-review/4918" target="_blank">https://wahis.woah.org/#/in-review/4918</a></p><p></p><p>''H-TYPE BSE AGENT IS TRANSMISSIBLE BY THE ORONASAL ROUTE''</p><p></p><p>This study demonstrates that the H-type BSE agent is transmissible by the oronasal route. These results reinforce the need for ongoing surveillance for classical and atypical BSE to minimize the risk of potentially infectious tissues entering the animal or human food chains.</p><p></p><p><a href="https://www.ars.usda.gov/research/publications/publication/?seqNo115=353094" target="_blank">https://www.ars.usda.gov/research/publications/publication/?seqNo115=353094</a></p><p>OIE Conclusions on transmissibility of atypical BSE among cattle</p><p></p><p>Given that cattle have been successfully infected by the oral route, at least for L-BSE, it is reasonable to conclude that atypical BSE is potentially capable of being recycled in a cattle population if cattle are exposed to contaminated feed. In addition, based on reports of atypical BSE from several countries that have not had C-BSE, it appears likely that atypical BSE would arise as a spontaneous disease in any country, albeit at a very low incidence in old cattle. In the presence of livestock industry practices that would allow it to be recycled in the cattle feed chain, it is likely that some level of exposure and transmission may occur. As a result, since atypical BSE can be reasonably considered to pose a potential background level of risk for any country with cattle, the recycling of both classical and atypical strains in the cattle and broader ruminant populations should be avoided. </p><p></p><p><a href="https://www.oie.int/fileadmin/SST/adhocreports/Bovine%20spongiform%20encephalopathy/AN/A_AhG_BSEsurv_RiskAss_Mar2019.pdf" target="_blank">https://www.oie.int/fileadmin/SST/adhocreports/Bovine spongiform encephalopathy/AN/A_AhG_BSEsurv_RiskAss_Mar2019.pdf</a></p><p></p><p>Annex 7 (contd) AHG on BSE risk assessment and surveillance/March 2019</p><p></p><p>34 Scientific Commission/September 2019</p><p></p><p>3. Atypical BSE</p><p></p><p>The Group discussed and endorsed with minor revisions an overview of relevant literature on the risk of atypical BSE being recycled in a cattle population and its zoonotic potential that had been prepared ahead of the meeting by one expert from the Group. This overview is provided as Appendix IV and its main conclusions are outlined below. With regard to the risk of recycling of atypical BSE, recently published research confirmed that the L-type BSE prion (a type of atypical BSE prion) may be orally transmitted to calves1 . In light of this evidence, and the likelihood that atypical BSE could arise as a spontaneous disease in any country, albeit at a very low incidence, the Group was of the opinion that it would be reasonable to conclude that atypical BSE is potentially capable of being recycled in a cattle population if cattle were to be exposed to contaminated feed. Therefore, the recycling of atypical strains in cattle and broader ruminant populations should be avoided.</p><p></p><p>The Group acknowledged the challenges in demonstrating the zoonotic transmission of atypical strains of BSE in natural exposure scenarios. Overall, the Group was of the opinion that, at this stage, it would be premature to reach a conclusion other than that atypical BSE poses a potential zoonotic risk that may be different between atypical strains.</p><p></p><p>4. Definitions of meat-and-bone meal (MBM) and greaves</p><p></p><p>snip...</p><p></p><p>REFERENCES</p><p></p><p>SNIP...END SEE FULL TEXT;</p><p></p><p><a href="http://web.oie.int/downld/PROC2020/A_SCAD_Sept2019.pdf" target="_blank">http://web.oie.int/downld/PROC2020/A_SCAD_Sept2019.pdf</a></p><p></p><p>Consumption of L-BSE–contaminated feed may pose a risk for oral transmission of the disease agent to cattle.</p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324790/" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324790/</a></p><p></p><p>Thus, it is imperative to maintain measures that prevent the entry of tissues from cattle possibly infected with the agent of L-BSE into the food chain.</p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310119/" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310119/</a></p><p></p><p>Brazil MAPA OMSA Confirms BSE TSE Prion atypical H-type</p><p></p><p>OFFICIAL NOTE - Map confirms that case of Bovine Spongiform Encephalopathy is atypical type H</p><p></p><p>Ministry is immediately adopting measures so that exports of Brazilian beef are reestablished as soon as possible</p><p></p><p>Published on 03/02/2023 22:18 Updated on 03/03/2023 00:08</p><p></p><p><a href="https://www.gov.br/agricultura/pt-br/assuntos/noticias/nota-oficial-mapa-confirma-que-caso-de-encefalopatia-espongiforme-bovina-e-atipico" target="_blank">https://www.gov.br/agricultura/pt-br/assuntos/noticias/nota-oficial-mapa-confirma-que-caso-de-encefalopatia-espongiforme-bovina-e-atipico</a></p><p></p><p>Brazil Confirms BSE Mad Cow Case, Strain not known yet</p><p></p><p>OFFICIAL NOTE </p><p></p><p>Mapa adopts measures on BSE case in Brazil </p><p></p><p>Meat for market consumption is not affected by confirmation </p><p></p><p>Published on 02/22/2023 8:15 pm Updated on 02/22/2023 9:51 pm </p><p></p><p><a href="https://www.gov.br/agricultura/pt-br/assuntos/noticias/mapa-adota-providencias-sobre-caso-de-eeb-no-brasil-1" target="_blank">https://www.gov.br/agricultura/pt-br/assuntos/noticias/mapa-adota-providencias-sobre-caso-de-eeb-no-brasil-1</a></p><p></p><p>Brazil Suspected case of bovine spongiform encephalopathy</p><p></p><p>COMUNICADO</p><p></p><p>Caso suspeito de Encefalopatia Espongiforme Bovina </p><p></p><p>para Copiar para área de transferência Publicado em 20/02/2023 15h36 </p><p></p><p>Atualizado em 20/02/2023 15h39 O</p><p></p><p><a href="https://www.gov.br/agricultura/pt-br/assuntos/noticias/caso-suspeito-de-encefalopatia-espongiforme-bovina" target="_blank">https://www.gov.br/agricultura/pt-br/assuntos/noticias/caso-suspeito-de-encefalopatia-espongiforme-bovina</a></p><p></p><p>2023/01/18</p><p></p><p>EVENT 4918</p><p></p><p>Brazil - Bovine spongiform encephalopathy</p><p></p><p><a href="http://https//wahis.woah.org/#/in-event/4918/dashboard" target="_blank">https://wahis.woah.org/#/in-event/4918/dashboard</a></p></blockquote><p></p>
[QUOTE="flounder, post: 1792057, member: 3519"] WAHIS Brazil Bovine spongiform encephalopathy Follow up report 1 [FINAL] Brazil - Bovine spongiform encephalopathy - Follow up report 1 [FINAL] GENERAL INFORMATION COUNTRY/TERRITORY OR ZONE COUNTRY/TERRITORY ANIMAL TYPE TERRESTRIAL DISEASE CATEGORY OIE-listed EVENT ID 4918 DISEASE Bovine spongiform encephalopathy CAUSAL AGENT Bovine spongiform encephalopathy prion, atypical strain, H-type GENOTYPE / SEROTYPE / SUBTYPE - START DATE 2023/01/18 REASON FOR NOTIFICATION Recurrence of an eradicated disease DATE OF LAST OCCURRENCE 2021/09/03 CONFIRMATION DATE 2023/02/22 EVENT STATUS Resolved END DATE 2023/03/03 SELF-DECLARATION NO REPORT INFORMATION REPORT NUMBER Follow-up report 1 REPORT ID FUR_159644 REPORT REFERENCE - REPORT DATE 2023/03/05 REPORT STATUS Validated NO EVOLUTION REPORT - EPIDEMIOLOGY SOURCE OF EVENT OR ORIGIN OF INFECTION Unknown or inconclusive EPIDEMIOLOGICAL COMMENTS On March 3rd, 2023, the National Centre for Animal Diseases/Canadian Food Inspection Agency (NCAD/CFIA), Lethbridge Laboratory, WOAH reference laboratory, issued a conclusive result of the Western Blotting test with atypical H-type BSE detected. This is the sixth case of atypical H-type BSE registered in Brazil in more than 25 years of surveillance for the disease. Brazil has never diagnosed a classical BSE case, maintaining, since 2012, official recognition by the WOAH as a country of negligible risk for the disease. The investigation has been completed. QUANTITATIVE DATA SUMMARY MEASURING UNIT Animal Species Susceptible Cases Deaths Killed and Disposed of Slaughtered/ Killed for commercial use Vaccinated Cattle (DOMESTIC) NEW------ TOTAL160 1 0 1 0 0 DIAGNOSTIC DETAILS CLINICAL SIGNS YES METHOD OF DIAGNOSTIC Diagnostic test Test name Laboratory Species sampled Number of outbreaks sampled First result date Latest result date Result Antigen detection Western blot (Ag Western blot) Canadian Food Inspection Agency (CFIA), National Centre for Animal Disease (NCAD), Lethbridge Laboratory Cattle 1 2023/03/03 2023/03/03 Positive Immunohistochemistry (IHC) Laboratorio Federal de Defesa Agropecuária - PE Cattle 1 2023/02/22 2023/02/22 Positive CONTROL MEASURES AT EVENT LEVEL CONTROL MEASURES AT EVENT LEVEL DOMESTIC ANIMALS WILD ANIMALS Official disposal of carcasses, by-products and waste Applied Screening Applied Selective killing and disposal Applied Traceability Applied PREVIOUSLY REPORTED OUTBREAKS OB_114504 - 15042080057 - MARABÁ [URL]https://wahis.woah.org/#/in-review/4918[/URL] ''H-TYPE BSE AGENT IS TRANSMISSIBLE BY THE ORONASAL ROUTE'' This study demonstrates that the H-type BSE agent is transmissible by the oronasal route. These results reinforce the need for ongoing surveillance for classical and atypical BSE to minimize the risk of potentially infectious tissues entering the animal or human food chains. [URL]https://www.ars.usda.gov/research/publications/publication/?seqNo115=353094[/URL] OIE Conclusions on transmissibility of atypical BSE among cattle Given that cattle have been successfully infected by the oral route, at least for L-BSE, it is reasonable to conclude that atypical BSE is potentially capable of being recycled in a cattle population if cattle are exposed to contaminated feed. In addition, based on reports of atypical BSE from several countries that have not had C-BSE, it appears likely that atypical BSE would arise as a spontaneous disease in any country, albeit at a very low incidence in old cattle. In the presence of livestock industry practices that would allow it to be recycled in the cattle feed chain, it is likely that some level of exposure and transmission may occur. As a result, since atypical BSE can be reasonably considered to pose a potential background level of risk for any country with cattle, the recycling of both classical and atypical strains in the cattle and broader ruminant populations should be avoided. [URL]https://www.oie.int/fileadmin/SST/adhocreports/Bovine%20spongiform%20encephalopathy/AN/A_AhG_BSEsurv_RiskAss_Mar2019.pdf[/URL] Annex 7 (contd) AHG on BSE risk assessment and surveillance/March 2019 34 Scientific Commission/September 2019 3. Atypical BSE The Group discussed and endorsed with minor revisions an overview of relevant literature on the risk of atypical BSE being recycled in a cattle population and its zoonotic potential that had been prepared ahead of the meeting by one expert from the Group. This overview is provided as Appendix IV and its main conclusions are outlined below. With regard to the risk of recycling of atypical BSE, recently published research confirmed that the L-type BSE prion (a type of atypical BSE prion) may be orally transmitted to calves1 . In light of this evidence, and the likelihood that atypical BSE could arise as a spontaneous disease in any country, albeit at a very low incidence, the Group was of the opinion that it would be reasonable to conclude that atypical BSE is potentially capable of being recycled in a cattle population if cattle were to be exposed to contaminated feed. Therefore, the recycling of atypical strains in cattle and broader ruminant populations should be avoided. The Group acknowledged the challenges in demonstrating the zoonotic transmission of atypical strains of BSE in natural exposure scenarios. Overall, the Group was of the opinion that, at this stage, it would be premature to reach a conclusion other than that atypical BSE poses a potential zoonotic risk that may be different between atypical strains. 4. Definitions of meat-and-bone meal (MBM) and greaves snip... REFERENCES SNIP...END SEE FULL TEXT; [URL]http://web.oie.int/downld/PROC2020/A_SCAD_Sept2019.pdf[/URL] Consumption of L-BSE–contaminated feed may pose a risk for oral transmission of the disease agent to cattle. [URL]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324790/[/URL] Thus, it is imperative to maintain measures that prevent the entry of tissues from cattle possibly infected with the agent of L-BSE into the food chain. [URL]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310119/[/URL] Brazil MAPA OMSA Confirms BSE TSE Prion atypical H-type OFFICIAL NOTE - Map confirms that case of Bovine Spongiform Encephalopathy is atypical type H Ministry is immediately adopting measures so that exports of Brazilian beef are reestablished as soon as possible Published on 03/02/2023 22:18 Updated on 03/03/2023 00:08 [URL]https://www.gov.br/agricultura/pt-br/assuntos/noticias/nota-oficial-mapa-confirma-que-caso-de-encefalopatia-espongiforme-bovina-e-atipico[/URL] Brazil Confirms BSE Mad Cow Case, Strain not known yet OFFICIAL NOTE Mapa adopts measures on BSE case in Brazil Meat for market consumption is not affected by confirmation Published on 02/22/2023 8:15 pm Updated on 02/22/2023 9:51 pm [URL]https://www.gov.br/agricultura/pt-br/assuntos/noticias/mapa-adota-providencias-sobre-caso-de-eeb-no-brasil-1[/URL] Brazil Suspected case of bovine spongiform encephalopathy COMUNICADO Caso suspeito de Encefalopatia Espongiforme Bovina para Copiar para área de transferência Publicado em 20/02/2023 15h36 Atualizado em 20/02/2023 15h39 O [URL]https://www.gov.br/agricultura/pt-br/assuntos/noticias/caso-suspeito-de-encefalopatia-espongiforme-bovina[/URL] 2023/01/18 EVENT 4918 Brazil - Bovine spongiform encephalopathy [URL='http://https//wahis.woah.org/#/in-event/4918/dashboard']https://wahis.woah.org/#/in-event/4918/dashboard[/URL] [/QUOTE]
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WAHIS Brazil Bovine spongiform encephalopathy Follow up report 1 [FINAL]
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